Acquired Thrombotic Thrombocytopenic Purpura: a rare disease associated Acquired with BNT162b2 vaccine
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چکیده
منابع مشابه
A case of Acquired Thrombotic Thrombocytopenic Purpura without Renal Dysfunction
Objective: Thrombotic thrombocytopenic purpura (TTP) is the most malignant variant of microangiopathy that usually presents by typical symptoms including thrombocytopenia, hemolytic anemia, neurological abnormalities, fever and renal impairment. Report of the Case: We report a 12-year-old male presented by cytopenia, fever, purpura on his extremities, seizure and lethargy. Peripheral blood sm...
متن کاملCaplacizumab for Acquired Thrombotic Thrombocytopenic Purpura.
BACKGROUND Acquired thrombotic thrombocytopenic purpura (TTP) is caused by aggregation of platelets on ultralarge von Willebrand factor multimers. This microvascular thrombosis causes multiorgan ischemia with potentially life-threatening complications. Daily plasma exchange and immunosuppressive therapies induce remission, but mortality and morbidity due to microthrombosis remain high. METHOD...
متن کاملa case of acquired thrombotic thrombocytopenic purpura without renal dysfunction
objective: thrombotic thrombocytopenic purpura (ttp) is the most malignant variant of microangiopathy that usually presents by typical symptoms including thrombocytopenia, hemolytic anemia, neurological abnormalities, fever and renal impairment. report of the case: we report a 12-year-old male presented by cytopenia, fever, purpura on his extremities, seizure and lethargy. peripheral blood smea...
متن کاملAcquired Thrombotic Thrombocytopenic Purpura in a Patient with Pernicious Anemia
Introduction. Acquired thrombotic thrombocytopenic purpura (TTP) has been associated with different autoimmune disorders. However, its association with pernicious anemia is rarely reported. Case Report. A 46-year-old male presented with blood in sputum and urine for one day. The vitals were stable. The physical examination was significant for icterus. Lab tests' results revealed leukocytosis, m...
متن کاملPathogenicity of Anti-ADAMTS13 Autoantibodies in Acquired Thrombotic Thrombocytopenic Purpura☆
BACKGROUND Acquired thrombotic thrombocytopenic purpura (TTP) is an autoimmune disease in which anti-ADAMTS13 autoantibodies cause severe enzyme deficiency. ADAMTS13 deficiency causes the loss of regulation of von Willebrand factor multimeric size and platelet-tethering function, which results in the formation of disseminated microvascular platelet microthrombi. Precisely how anti-ADAMTS13 auto...
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ژورنال
عنوان ژورنال: Journal of Thrombosis and Haemostasis
سال: 2021
ISSN: 1538-7933,1538-7836
DOI: 10.1111/jth.15420